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dc.contributor.authorCuartas Quo, Diana Cristina
dc.contributor.authorAgudelo Ortiz, Alejandra
dc.contributor.authorGomez-Mercado, Carlos Alberto
dc.contributor.authorMejía Sandoval, Gregory
dc.contributor.authorArias Gutiérrez, María Patricia
dc.contributor.authorMoreno, Ricardo D.
dc.contributor.authorPatiño-García, Daniel
dc.contributor.authorOrellana, Renan
dc.date.accessioned2021-05-05T15:01:08Z
dc.date.available2021-05-05T15:01:08Z
dc.date.issued2021-05-04
dc.identifier.urihttp://hdl.handle.net/10946/5213
dc.description.abstractObesogens are endocrine disruptors due to their ability to interrupt hormone systems and cause adverse developmental, reproductive, neurological, and immunological effects in mammals, altering normal lipid metabolism and adipogenesis. The study used an in vivo mice models to evaluate the effects of in utero and postnatal exposure to obesogens on adipose cellularity and adipocyte area in offspring. The experimental groups included low & high dosages of obesogens, a mixed dosage and a control. The number and area of adipocytes was then evaluated. Results demonstrated a significant difference in cell number and area even at the lowest dosages, indicating that even exposure to low quantities of obesogens cause measurable changes in adipose tissue. In future studies, it is important to continue research into the quantification of their effects, relating specific dosages of obesogens to their consequences on adipose tissue.spa
dc.language.isoen_USspa
dc.subjectBPAspa
dc.subjectDEHPspa
dc.subjectEndocrine disrupting chemicals (EDC)spa
dc.subjectObesogensspa
dc.subjectPrenatal exposurespa
dc.titleEvaluation of the effect of exposure to endocrine disruptors on the area and number of adipocytes per unit of area in abdominal tissue in micespa
dc.typeInforme de investigacionspa
dc.typeTrabajo de Gradospa
dc.rights.licenseRestringidospa


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