Histopathologic findings in uteri and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: a cross-sectional study
Date
2018
Authors
Maya Pulgarín, Daniel
González Domínguez, María Soledad
Aránzazu Taborda, Diego
Mendoza, Natalia
Maldonado Estrada, Juan Guillermo
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad CES
Abstract
Opinions on ovariohysterectomy (OHE) of bitches vary depending on region and country. In this descriptive, prospective cross-sectional study,
uterine tracts and ovaries exhibiting gross pathologic findings (n = 76) were collected post-surgery from a reference population of 3,600 bitches
(2.11% incidence) that underwent elective OHE during September to November 2013 and evaluated by histopathology examination. Data
were evaluated by using descriptive statistics and chi-squared tests. Bitches were of crossbred background with average age 5 years (range
0.6–8.0 years) and most were nulliparous (69.7%) with no anamnesis of reproductive diseases (81.6%). Frequencies of proestrus, estrus, and
diestrus were 42.1%, 6.6%, and 19.7%, respectively. The presence of mammary gland masses (5.3%) significantly correlated with
histopathologic findings in ovaries and age of the bitch (p ＜ 0.05). Predominant uterine histopathologies included cystic endometrial
hyperplasia, periglandular fibrosis, lymphoplasmocytary endometritis, and adenomyosis (19.7%, 14.5%, 4.0%, and 2.6%, respectively). In
ovaries, hyperplasia of rete ovarii, follicular cysts, oophoritis, adenoma of the rete ovarii, cysts of superficial structures, and granulosa cell
tumors (10.5%, 10.5%, 7.9%, 4.0%, 2.6%, and 2.6%, respectively) were observed. The results reveal the presence of subclinical pathologies
in healthy bitches, suggesting that OHE at an early age is beneficial for prevention of reproductive pathologies.
Description
Keywords
Canine neoplastic disease, Canine ovarian pathology, Cystic endometrial hyperplasia, Canine uterine pathology