A patient with 60, XY and disorders of sex development (DSD) in Gyr Breed Animal
Date
2018-11-27
Authors
Urrego Álvarez, Rodrigo Antonio
Giraldo Giraldo, Erika Tatiana
Benjumea Mesa, Juan David
Rendón Cardona, Yesid Alejandro
Posada Botero, Juan Carlos
Veloza Agudelo, Luis Carlos
Ramírez García, Francisco René
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad CES
Abstract
An atypical case of sexual development disorder, where the presence of an intersex evidenced in the physical examination, is described in a twin male bull of the Gyr breed. Initially, it was believed that the animal analyzed corresponded to a case of freemartins, having a feminine appearance. In addition, the physical examination of the animal evidenced several abnormalities, had feminized phenotype, smaller size, did not develop male gonads and had a highly developed clitoris in the form of the penis. However, the results of cytogenetic and molecular analysis suggest that the sexual disorder presented in the female is not a case of freemartins and that the female is actually a male who presented a case of intersex. Although in the macroscopic examination of the organs were observed rudiments of what could be vulva, uterine horns and ovaries; the histological evaluation does not show the presence of female cells in these tissues, but if a histological structure of the epididymis is observed. This is an unusual situation of disorders of sex development with genital tract anomalies in cattle, probably associated to a mutation in a gene involved in the proper development of the male gonad.
Description
Keywords
Intersex, XY, Disorders of sex development, Gyr breed animal