Abstract

Objective. To assess the effectiveness and describe the molecular mechanism involved in surgical methods used in accelerated orthodontics.Background. Several surgical methods have been developed to accelerate orthodontic tooth movement, in past few years various randomized controlled trials have been published and this controversial topic was in need of an actualization. Objective. To assess the effectiveness and describe the molecular mechanism involved in surgical methods used in accelerated orthodontics. Search methods. Electronic database searches (MEDLINE, EMBASE, The Cochrane Library, and LILACS) were performed until June 2018 using controlled terms identified in the articles included in the theoretical framework. Additional controlled and uncontrolled vocabulary was identified using the search tools provided by the databases according to the PICO question. Selection criteria. Articles were screened for randomized controlled trials using adjunctive surgical methods to accelerate orthodontic tooth movement, i.e. corticotomy, accelerated osteogenic orthodontics, periodontal distraction, corticision, piezopuncture, piezosurgery, piezocision and micro-osteoperforations; with the following primary outcome measures: velocity of tooth movement; distance of accumulated tooth movement; total treatment time; and levels of inflammatory and bone remodeling markers in saliva or gingival crevicular fluid. Data collection and analysis. Two independent authors evaluated the included articles using a standardized form to extract data, including quality indicators. Risk of bias was assessed using the Cochrane risk of bias tool.