Antioxidant and inhibitory capacity of tomato ethanolic extract against streptococcus mutans, Porphyromonas gingivalis, and Candida albicans

Mendoza Lara, Yeiner David; Arias Londoño, Mónica Andrea; Sánchez Garzón, Juliana del Pilar; Rojas Vahos, Diego Fernando; Robledo Sierra, Jairo

dc.contributor.author	Mendoza Lara, Yeiner David
dc.contributor.author	Arias Londoño, Mónica Andrea
dc.contributor.author	Sánchez Garzón, Juliana del Pilar
dc.contributor.author	Rojas Vahos, Diego Fernando
dc.contributor.author	Robledo Sierra, Jairo
dc.contributor.editor	Robledo Sierra, Jairo
dc.date.accessioned	2022-07-01T16:01:07Z
dc.date.available	2022-07-01T16:01:07Z
dc.date.issued	2022-06-22
dc.identifier.uri	https://hdl.handle.net/10946/6026
dc.description.abstract	Background: Tomato is a source of bioactive compounds, antimicrobials, and antioxidants. Tomato leaf preparations have been empirically used for anti-inflammatory, analgesic, antibiotic, and antiseptic purposes. However, the research on the potential activity of tomato leaf extracts against oral microorganisms and in the management of oropharyngeal infections is scarce. Objective: To investigate tomato leaf ethanolic extract’s antioxidant and growth inhibitory capacity against common oral pathogenic microorganisms, namely, Streptococcus mutans, Porphyromonas gingivalis, and Candida albicans. Methods: Ethanolic extracts were made from ‘Chonto’ tomato (Lycopersicon esculentum) leaves. The antimicrobial activity was measured with the microdilution technique using vancomycin and fluconazole as positive controls. The antioxidant capacity was measured with the ORAC assay using Trolox as a positive control. Results: We found a high percentage of growth inhibition (≥100%) against S. mutans and P. gingivalis at a concentration of 500 mg/L. However, the extract was ineffective in inhibiting the growth of C. albicans. Finally, we observed that the extract exerted a high antioxidant capacity (126%) compared to the positive control. Conclusions: This study provides new insights into the potential antimicrobial effect of tomato leaf extracts on common oral pathogenic bacteria, which may ultimately result in the development of new herbal products that might help prevent and treat oral infections, such as dental caries and periodontal disease. Our findings also support previous studies on the high antioxidant capacity of tomato leaf extracts.	spa
dc.language.iso	en	spa
dc.publisher	Universidad CES	spa
dc.relation.uri	https://revistas.udea.edu.co/index.php/vitae/article/view/349996
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Lycopersicon esculentum	spa
dc.subject	Tomato	spa
dc.subject	Ethanolic extract	spa
dc.subject	Streptococcus mutans	spa
dc.subject	Porphyromonas gingivalis	spa
dc.subject	Candida albicans	spa
dc.subject	Antioxidant capacity	spa
dc.title	Antioxidant and inhibitory capacity of tomato ethanolic extract against streptococcus mutans, Porphyromonas gingivalis, and Candida albicans	spa
dc.type	Articulo de revista	spa
dc.rights.license	Abierto	spa
dc.rights.cc	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.cc	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*