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dc.contributorZapata Ocampo, Paola Andrea
dc.contributor.authorVilla Jimenez, Isabel
dc.contributor.authorEscobar Libreros, Simón
dc.contributor.authorLoaiza Gutiérrez, Valentina
dc.contributor.authorHoyos Castañeda, Diana
dc.contributor.authorArias Londoño, Monica
dc.date.accessioned2023-11-09T17:26:33Z
dc.date.available2023-11-09T17:26:33Z
dc.date.issued2023-11-09
dc.identifier.urihttps://hdl.handle.net/10946/7862
dc.description.abstractOral contraceptives are one of the most widely used methods of pregnancy prevention. However, different symptomatologies have been attributed to their use. Studies have shown that prolonged use of oral contraceptives is related to an imbalance in the intestinal microbiota, negatively impacting the user's homeostasis. Specifically, the accumulation of these drugs in the intestine affects bacterial growth, leading to the possible development of multiple immunological, intestinal, metabolic, and other alterations. Nevertheless, the relationship between different pathologies and dysbiosis in the intestinal microbiota has not been completely characterized, making it difficult to correlate specific side effects of oral contraceptives on the microbiota. Therefore, the aim of this study was to evaluate the in vitro impact of eight concentrations of three oral contraceptives Yasminiq ®, Bellaface suave ®, and Microgynon ®, on the growth of the gut-beneficial bacteria Lactobacillus reuteri, Lactobacillus plantarum and Lactobacillus rhamnosus. Our results indicated no statisticastically significant differences between the concentrations of the three contraceptives used on L. reuteri and L. plantarum. These strains showed no significant growth inhibition when exposed to the different concentrations of the contraceptives. Conversely, L. rhamnosus showed susceptibility to all of the contraceptives. Particularly, the lowest concentrations of Bellaface ® showed the highest percentages of inhibition on L. rhamnosus.es_ES
dc.language.isoenes_ES
dc.publisherUniversidad CESes_ES
dc.subjectOral contraceptiveses_ES
dc.subjectGut microbiomees_ES
dc.subjectInhibitiones_ES
dc.subjectL. reuteries_ES
dc.subjectL. Plantarumes_ES
dc.subjectL. rhamnosuses_ES
dc.titleEffect of combined oral contraceptives on the in vitro growth of the beneficial gut bacteria Lactobacillus reuteri, Lactobacillus plantarum and Lactobacillus rhamnosuses_ES
dc.typeTrabajo de Gradoes_ES
dc.contributor.roleColaboradores_ES
dc.rights.accessrightsinfo:eu-repo/semantics/closedAccesses_ES
datacite.rightshttp://purl.org/coar/access_right/c_14cbes_ES


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